It would appear as if researchers have finally been able to come up with a genetics test that can be used in order to give an accurate estimate for when Alzheimer’s will effect a person. With reasonable accuracy, it can pinpoint the age that the sad disease will take hold.
The test takes into account your level of risk based off of 31 genetic markers. Those that score a high number on this test are much more likely to suffer from Alzheimer’s earlier on, while a lower score would mean that the disease wouldn’t take effect until a later time in a person’s life. The top 10% of participants were ranked as having a three times likelihood of developing the disease during the course of the study, which came true when these participants developed it an average of 10 years earlier than the lower 10% of participants.
University of California researcher Rahul Desikan led this project on an international level. He believes that the test would be most effective in determining whether or not a person will be effected by the disease later that same year. For an elderly person that doesn’t suffer from dementia, it may be able to pinpoint their risk of an early onset through genetic information obtained by the test.
The resulting score is the polygenic hazard score. This test was developed through a broad study that used a total of 70,000 participants. These participants included those that already had Alzheimer’s as well as those that were perfectly healthy.
We have known for quite some time that genetics is a big contributor of Alzheimer’s. About a quarter of all patients have had some form of family history with the disease, effecting a large portion of the population. Scientists believe that it is explained through the gene ApoE, which comes in a variety of three. It has been shown to be a strong influence on a person developing the disease.